Resident Population in South Carolina was 5373.55500 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in South Carolina reached a record high of 5373.55500 in January of 2023 and a record low of 1342.00000 in January of 1900. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in South Carolina - last updated from the United States Federal Reserve on April of 2024.