Resident Population in Onondaga County, NY was 467.87300 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Onondaga County, NY reached a record high of 474.92200 in January of 1993 and a record low of 452.74800 in January of 2007. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Onondaga County, NY - last updated from the United States Federal Reserve on May of 2024.