Resident Population in Brule County, SD was 5.31100 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Brule County, SD reached a record high of 5.87000 in January of 1970 and a record low of 5.06600 in January of 2006. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Brule County, SD - last updated from the United States Federal Reserve on May of 2024.